Glycerin USP Grade

Product Identifier

Glycerin USP Grade

Grade

USP Grade

CAS Number

56-81-5

Chemical Formula

C3H8O3

Molecular Weight

92.09 g/mol

Manufacturer

Alliance Chemical
204 South Edmond Street, Taylor, TX 76574

Emergency Phone

Chemtel 1-800-255-3924 (24/7)

Synonyms

Glycerol; glycerine; 1,2,3-propanetriol

Recommended Use

USP grade: humectant, solvent and sweetener in pharmaceutical, food, cosmetic and personal-care products; soap making.

Restrictions on Use

USP grade: for drug, food and cosmetic use at levels permitted by the applicable regulations (21 CFR 182.1320).

Signal Word

Not applicable

Hazard Statements

Not classified as hazardous under GHS based on available data.

Precautionary Statements

No specific GHS precautionary statements required.

Concentrations are nominal; lot-specific values appear on the Certificate of Analysis. Components not contributing to classification are omitted.

Eyes

Rinse with water. Get medical attention if irritation develops or persists.

Skin

Wash with soap and water. Get medical attention if irritation develops.

Inhalation

Move to fresh air if discomfort occurs.

Ingestion

Rinse mouth with water. Get medical attention if you feel unwell.

Most Important Symptoms and Effects

• No specific symptoms are expected from the hazards identified in Section 2.

Immediate Medical Attention and Special Treatment

• Treat symptomatically. Get medical attention if symptoms develop or persist.

Suitable Extinguishing Media

Use water spray, alcohol-resistant foam, dry chemical, or CO2. Use measures appropriate to local circumstances.

Unsuitable Extinguishing Media

Do not use a solid water stream as it may scatter and spread fire.

Specific Hazards Arising from the Chemical

Containers may rupture when heated.

Protective Equipment

Wear self-contained breathing apparatus and full protective clothing.

Hazardous Combustion Products

Acrolein (a severe irritant) when overheated; carbon monoxide and carbon dioxide on combustion.

Personal Precautions

Wear safety glasses and gloves for cleanup. Spills can make floors slippery.

Environmental Precautions

Avoid releasing large quantities to drains or waterways.

Containment & Cleanup

Absorb or wipe up, then rinse the area with water. Dispose of according to local regulations.

Safe Handling

Use with adequate ventilation. Avoid contact with skin, eyes, and clothing. Wash thoroughly after handling. Keep container closed when not in use.

Safe Storage

Store in a cool, dry, well-ventilated area. Keep away from incompatible materials (see Section 10). Keep containers tightly closed.

Specific Storage Precautions

Keep tightly closed (hygroscopic) in a dry place away from strong oxidizers. Stainless steel, aluminum or polyethylene containers.

Occupational Exposure Limits

Engineering Controls

General ventilation is normally adequate.

Eye/Face Protection

Safety glasses are recommended.

Skin Protection

Gloves are recommended for prolonged or repeated contact.

Respiratory Protection

Not normally required.

Exposure limits sourced from NIOSH Pocket Guide, OSHA 29 CFR 1910.1000 and ACGIH TLVs.

Appearance

Clear, colorless, thick viscous liquid

Odor

Odorless

Odor Threshold

No data available

pH

Neutral (5.5–8 in aqueous solution)

Melting Point / Freezing Point

18–20 °C (64–68 °F); readily supercools and stays liquid

Boiling Point

290 °C (554 °F), with decomposition

Flash Point

160–199 °C (320–390 °F)

Evaporation Rate

No data available

Flammability (solid, gas)

No data available

Upper/Lower Flammability or Explosive Limits

LEL 0.9–2.7% / UEL 19% (v/v in air)

Vapor Pressure

Below 0.001 hPa at 20 °C (negligible)

Vapor Density

3.2 (air = 1)

Relative Density

1.263 at 20/20 °C (water = 1)

Solubility

Completely miscible with water; hygroscopic

Partition Coefficient (n-octanol/water)

log Kow -1.75

Auto-ignition Temperature

370–429 °C (698–804 °F)

Decomposition Temperature

No data available

Viscosity

About 1,400 mPa·s at 20 °C

Particle Characteristics

Not applicable

Form

Liquid

Density

1.2606 g/cm³ at 20 °C

Refractive Index

1.470-1.475

Values shown reflect product-specific canonical data. Lot-specific ranges may vary; see the Certificate of Analysis for the shipped lot.

Reactivity

Not reactive under normal conditions of use and storage.

Chemical Stability

Stable under recommended storage conditions.

Possibility of Hazardous Reactions

None under normal processing conditions.

Conditions to Avoid

Strong heating (decomposes near 290 °C to acrolein); contact with strong oxidizers; moist air (hygroscopic).

Incompatible Materials

Strong oxidizing agents (violent reaction with potassium permanganate, chromium trioxide and similar); strong bases.

Hazardous Decomposition Products

Acrolein (a severe irritant) when overheated; carbon monoxide and carbon dioxide on combustion.

See below for route-specific acute toxicity data.

Likely Routes of Exposure

Inhalation, skin contact, eye contact, ingestion.

Symptoms

• No specific symptoms are expected from the hazards identified in Section 2.

Delayed and Chronic Effects

• No delayed or chronic effects identified beyond the classification in Section 2.

Carcinogen Classification

Ecotoxicity

Daphnia EC50: > 10000 mg/L (24 h, Daphnia magna (≤24 h), formulated product; 24-h window); Fish LC50: > 5000 mg/L (24 h, Goldfish (modified ASTM D 1345); 24-h window)

Persistence & Degradability

Not persistent; low soil/sediment adsorption, not expected to volatilize

Bioaccumulative Potential

log Kow −1.76

Mobility in Soil

Very high mobility in soil (estimated Koc ≈ 1)

Dispose of contents/container in accordance with applicable federal, state, and local regulations. Do not dispose of into drains or waterways.

EPA RCRA Waste Codes

Not a listed or characteristic hazardous waste.

Not regulated for transport under US DOT 49 CFR Subchapter C, IMDG, or IATA DGR.

CERCLA Reportable Quantity (RQ)

Not a CERCLA hazardous substance (no RQ); not an EPCRA Section 313 chemical.

SARA 311/312 hazard categories correspond to the GHS classification in Section 2. Data retrieved as of: California Proposition 65 2026-11-02; US EPA TSCA Active Inventory 2026-11-02; EPCRA SARA 313 (TRI) 2026-11-02.

Revision Date

2026-10-20

Format

16-section format per OSHA HCS 2024 (29 CFR 1910.1200, Appendix D), aligned with GHS Rev. 7.