Industrial chemicals · Taylor, TX
Technical Data Sheet

Technical Data Sheet

Propylene Glycol 20% USP GRADE

USP · 20%

CAS Number
57-55-6
Alliance Code
propylene-glycol-20-usp-grade
Generated
2026-09-11
Revision
1.3
Reviewed
2026-06-17 · Andre Taki
2D chemical structure of Propylene Glycol 20% USP GRADE
Structure · PubChem
Last reviewed 2026-06-17 by Andre Taki, DOT Hazmat Specialist.

Identity & Composition

Product Name
Propylene Glycol 20% USP GRADE
Alliance Code
propylene-glycol-20-usp-grade
Grade
USP
Concentration
20%
CAS Number
57-55-6PubChem
Formula
C3H8O2PubChem
Molecular Weight
76.09PubChem
Product Type
mixture

Specifications

TestSpecificationTypicalMethodSource
Assay19.0 - 21.0 %, by volume20.0 %Interpreted
Propylene glycol concentration19.0 - 21.0 % v/v20.0 %Interpreted
Dilution waterPurified Water USP; conductivity ≤ 1.3 µS/cm @ 25 °CPasses testUSP <1231> / conductivity USP <645>Interpreted
Aciditynot more than 0.04 mL of 0.10 N sodium hydroxide0.01USP monograph titration, 0.10 N NaOHInterpreted
Microbial enumerationTAMC ≤ 100 CFU/mL; TYMC ≤ 10 CFU/mLPasses testUSP <61>Interpreted
Chloride0.0015% max0.0000062 %USP <221>Interpreted
Heavy metals1 ppm max0.1 ppmUSP <231>Interpreted
Iron0.11 ppm max0.01 ppmHOC 0290Interpreted
Limit of Diethylene Glycol0.021% max0.00062 %GC, flame ionization detector, 0.53-mm x 30-m fused-silica G43 column, 2,2,2-trichloroethanol internal standardInterpreted
Limit of Ethylene Glycol0.021% max0.00041 %GC, flame ionization detector, 0.53-mm x 30-m fused-silica G43 column, 2,2,2-trichloroethanol internal standardInterpreted
Residue on ignition0.0016 wt% max0.0001 wt%Ignition of 50 g, residue moistened with 0.5 mL sulfuric acid and ignited to constant weightInterpreted
Sulfate0.0013% max0.0001 %USP <221>Interpreted
arsenic0.21 ppm max0.0041 ppmInterpreted
dpg0.021 % max0.0062 %Interpreted
pb0.21 mg/kg max0.0021 mg/kgInterpreted
meg0.00021 % max0.0001 %Interpreted
po0.00021 % max0.000041 %Interpreted
tpg0.0062 % max0.0012 %Interpreted
residue0.001 % max0.00021 %Interpreted
Identification A (Infrared Absorption)Infrared Absorption 〈197F〉 on undried specimenPasses testUSP <197F>Interpreted
Residual solventsPassPasses testUSP <467>Interpreted
Suspended matterPassPasses testHOC 0171Interpreted
Composition20 % propylene glycol / 80 % deionized water, by volumeConformsBy formulation; confirmed by specific gravityInterpreted
Freeze point18.7 °F (-7.4 °C) max18.7 °F (-7.4 °C)ASTM D1177Interpreted

Specification values are guaranteed limits. Typical values are representative of production lots and are not guaranteed. Lot-specific certificates of analysis ship with every order.

Available GradesSame CAS, alternate grades and concentrations

GradeConcentrationTypical AssaySKUTDS
This grade USP20%currentcurrent
60%propylene-glycol-60-inhibitedView TDS →
Technical60%propylene-glycol-60-technical-gradeView TDS →
USP60%propylene-glycol-60-usp-gradeView TDS →
USP Grade50%50-propylene-glycol-usp-gradeView TDS →
Technical Grade40%40-propylene-glycol-technical-gradeView TDS →
USP Grade40%40-propylene-glycol-usp-gradeView TDS →
20%propylene-glycol-20-inhibitedView TDS →
Technical20%propylene-glycol-20-technical-gradeView TDS →
Technical Gradepropylene-glycol-technical-gradeView TDS →
USP Gradepropylene-glycol-usp-gradeView TDS →

Typical assay shown is the rolling-window mean from the sibling product's most recent lots. Grade selection drives downstream end-use — verify the sibling grade matches your specification before substitution.

Physical & Chemical Properties

PropertyValueSource
AppearanceClear, colorless to pale liquidPublished reference
Color10 APHA (maximum)Interpreted
OdorPassInterpreted
pHEssentially neutral (unbuffered blend)Published reference
Specific Gravity (20 °C)1.022 (20 °C)Published reference
Density1.022 g/mL at 20 °CPublished reference
Boiling Point~101 °CPublished reference
Melting Point-7 °C (freeze / crystallization onset)Published reference
Flash PointNot flammable (aqueous solution)Published reference
Solubility (water)Miscible with waterPublished reference

Regulatory & Transport

DOT / 49 CFR

UN Number
Not regulatedAdjudicated
Hazard Class
Not regulatedAdjudicated
Packing Group
Not regulatedAdjudicated
Proper Shipping Name
Not regulatedAdjudicated

GHS / OSHA HazCom 2012

Signal Word
Not regulatedAdjudicated
H-Codes (Hazard Statements)
Not applicableECHA CLP Annex VI
P-Codes (Precautionary Statements)
Not applicableECHA CLP Annex VI

Occupational Exposure Limits

OSHA PEL (29 CFR 1910.1000)
no canonical
ACGIH TLV
no canonical
NIOSH REL
no canonical
NIOSH IDLH
no canonical

Transport descriptions reflect 49 CFR 172.101 lookup at time of publication. Sourced data: ECHA CLP Annex VI for harmonised classifications, NIOSH Pocket Guide for REL/IDLH, OSHA Z-Tables for PEL. Always verify against the latest regulatory text before shipment-critical decisions.

Supplier Qualification Packet

One zipped download containing the TDS, SDS, latest lot COA (when available), and a fresh Letter of Continuing Guaranty for Propylene Glycol 20% USP GRADE. Every file included is SHA-256 hashed and listed in a manifest your QA team can audit.

Download audit packet

Application Guidance

Propylene Glycol 20% USP GRADE (USP) is a glycol-based heat-transfer and freeze-protection fluid. Concentration sets the freeze and burst protection; the inhibitor package sets how long the system stays protected from corrosion.

  • Closed-loop heat transfer and process cooling
  • Data-centre and chilled-water freeze protection
  • HVAC hydronic loops and glycol makeup
  • Freeze and burst protection for idle or seasonal systems
  • Humectant and carrier applications (USP/food-grade propylene glycol only)

Verify concentration against the required freeze and burst protection, and confirm elastomer and metallurgy compatibility for the service temperature. Ethylene glycol is toxic by ingestion and must not be used where incidental food or potable contact is possible — specify a propylene glycol grade for those services.

Storage & Handling

Recommended Storage
Cool, dry, well-ventilated area in tightly sealed original containers. Neat glycols are combustible liquids with high flash points (roughly 99–111 °C) and do not require a solvent store; aqueous blends will not sustain combustion. Protect inhibited coolants from contamination and from freezing below their stated protection point.Class-level guidance — not product-specific; the SDS controls.
Handling Precautions
Chemical-resistant gloves and splash goggles. Ethylene glycol grades are toxic by ingestion and must be kept away from food, drink and animals; propylene glycol grades are not. Avoid contact with hot surfaces and hot process equipment. Inhibitor packages deplete in service — monitor rather than top up blindly.Class-level guidance — not product-specific; the SDS controls.
Incompatibilities
Strong oxidizers, strong acids and strong bases. Galvanized (zinc) surfaces are attacked by many inhibited coolant packages. Verify elastomer and gasket compatibility for the service temperature; EPDM is standard for glycol/water service.Class-level guidance — not product-specific; the SDS controls.
Shelf Life
Consult Technical Services for product-specific shelf life

For full hazard, PPE, and emergency response guidance, refer to the Safety Data Sheet (SDS) for this product. The SDS controls in all cases where guidance differs.

Packaging & Logistics

Shipping Description (US DOT)

Not regulated for transport.

Confirm against shipping documents and carrier requirements before tender.

NMFC Class
55

Revision History

Last reviewed 2026-06-17 by Andre Taki, DOT Hazmat Specialist.

VersionDateChangeTrigger
1.32026-09-09Canonical data updated: 1 field changed via the provenance/adjudication pipeline.
  • physicalProperties· canonical change (coa.data_provenance / adjudication)
canonical_change
1.22026-07-24Canonical data updated: 1 field changed via the provenance/adjudication pipeline.
  • physicalProperties· canonical change (coa.data_provenance / adjudication)
canonical_change
1.12026-06-17Canonical data re-verified: 3 fields updated against independent vendor SDSs, CLP Annex VI, 49 CFR, and OSHA HazCom 2024 (GHS classification, hazard/precautionary codes, signal word, physical properties as applicable).
  • countryOfOrigin· canonical adjudication / reground (coa.data_provenance)
  • dotSubsidiaryHazardClass· canonical adjudication / reground (coa.data_provenance)
  • hsCode· canonical adjudication / reground (coa.data_provenance)
canonical_change
1.02026-05-20Initial URL-first TDS published from canonical chemistry registry.initial

This Technical Data Sheet is provided for technical reference. The Safety Data Sheet (SDS) controls in all cases where guidance differs. Values reflect Alliance Chemical canonical data at time of generation; subsequent revisions are recorded in the Revision History above.